Two Children With Steroid-Resistant Significant Proteinuria Due to Nonsense Mutations of the TRIM8 Gene: A Case Report and Literature Review

BackgroundTRIM8 gene mutations have been reported as the genetic basis of autosomal dominant (AD) neuro-renal syndrome in children, which presents with Amplifier epileptic encephalopathy, focal segmental glomerulosclerosis (FSGS), developmental delay, and mental retardation.In this study, we report the cases of two children with significant protein

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Profile and outcome of congenital heart diseases in children: A preliminary experience from a tertiary center in Sokoto, North Western Nigeria

Aims and Objectives: Congenital heart diseases (CHDs) contribute significantly to childhood morbidity and mortality in many developing countries, largely due to late recognition and lack of skill and facilities for definitive intervention.Though data is available from other parts of the country, little is known about the pattern of CHD in the study

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An N=1 $$ mathcal{N}=1 $$ 3d-3d correspondence

Abstract M5-branes on an associative three-cycle M 3 in a G 2-holonomy manifold give rise to a 3d N=1 $$ mathcal{N}=1 $$ supersymmetric gauge theory, TN=1M3 $$ {T}_{mathcal{N}=1}left[{M}_3 ight] $$.We propose an N=1 $$ mathcal{N}=1 $$ 3d-3d correspondence, based on two observables of these theories: the Witten index and the S 3-partition function.T

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